UltraGen Archives

* currently only open to reviewers

1. UltraGen models

1.1 UltraGen source code and pre-trained model

1.1.1 UltraGen source code and pre-trained model
File File Size MD5 Digest
UltraGen.pkl 127.84MB ecb2d2864a25e85a86bcf73d981645a5
UltraGen_source_code.zip 373.97KB 81466cae5d7a9b932190b4cd5621dcc4

1.2 UltraGen fine-tuned model for artificial RNA evolution

1.2.1 RNA aptamer ranking prediction for small molecule targets
File File Size MD5 Digest
UltraGen_System_Ranking_for_BC.pkl 127.84MB 308f32ad7c2603f5101de09cb9e147fb
UltraGen_System_Ranking_for_DAse.pkl 127.83MB cc40753fb98f7602ab8577939408786c
UltraGen_System_Ranking_for_MI.pkl 127.83MB ea82a652309d53467d7a504ad0c84a30
UltraGen_System_Ranking_for_PR.pkl 127.84MB 3598f97a8ca9828912ab07f8d3ab9518
1.2.2 RNA aptamer ranking prediction for protein targets
File File Size MD5 Digest
UltraGen_System_Ranking_for_RBM24.pkl 127.83MB 37e18e4adc11f4407314264bb97d8e5f
UltraGen_System_Ranking_for_RT.pkl 127.84MB 099a53fd8e05f31c679f7e972d3f788e
UltraGen_System_Ranking_for_S15.pkl 127.83MB 41eb2b5ad8582978916dcb0ddda2412f
UltraGen_System_Ranking_for_TARDBP.pkl 127.84MB 5b7d5ddcb6b4e1f4b316695a8facbcf9
1.2.3 RNA aptamer ranking prediction for (multi)cellular targets
File File Size MD5 Digest
UltraGen_System_Ranking_for_CHO-K1.pkl 127.84MB 2f9dcc94ff64016e96b31ba5dff66a04
UltraGen_System_Ranking_for_ISLETS.pkl 127.83MB 26aff4cdebda49fd06fdd94930c00790
UltraGen_System_Ranking_for_MDSC.pkl 127.84MB 543247faa2a403bc57723bfc24ba638d
UltraGen_System_Ranking_for_TNBC.pkl 127.84MB e98036fb839e6614c84296b2e5c5c18a

1.3 UltraGen fine-tuned model for natural RNA evolution

1.3.1 Classifying human tissue-specific hallmarks of 3'-untranslated RNA
File File Size MD5 Digest
UltraGen_3UTR.pkl 127.87MB e3a51d087bd493cb5b19b58507e20aad

1.4 UltraGen variants with broader pre-training source

1.4.1 Pre-training from scratch utilizing diverse pre-training datasets
File File Size MD5 Digest
UltraGen_source_SiR.pkl 127.82MB 947418c37505a11ceda783b2e0bbe088
UltraGen_source_nsp12.pkl 127.82MB cf299b09f75dab00c67d39d4a53a55e1
1.4.2 Continued pre-training of the UltraGen base model utilizing diverse pre-training datasets
File File Size MD5 Digest
UltraGen_3UTR.pkl 127.82MB f6e33b8a5f123aa72dbc21125ded7787
UltraGen_molecule.pkl 127.82MB 2128d659b8152ec709650d69ff1b9a24
UltraGen_plus.pkl 127.82MB db8a9855d5efd6305846f08fcc4637a2

2. Datasets

2.1 Pre-trained dataset

2.1.1 UltraGen pre-trained data (UltraSelex data targeting for Fluorogenic Silicon Rhodamine with tRNA Blocking System)
File File Size MD5 Digest
SiR-B_top_auc_10M.zip 223.18MB 98ac9e28778f9b12234549e501987588

2.2 Dataset for fine-tuning in artificial RNA evolution

2.2.1 SELEX data for small molecule targets
File File Size MD5 Digest
RNA_SELEX_data_for_BC.zip 1.26GB fe93cb30cd0ea6b10259a6848265849c
RNA_SELEX_data_for_DAse.zip 19.4MB 4d6a2928920e00cdd3db0f95ca4c2e4a
RNA_SELEX_data_for_MI.zip 44.3MB 6ce52426273bdd16f53bc045366528df
RNA_SELEX_data_for_PR.zip 320.15MB 5835a6d5d57aaf16e8f1d68fdf693ef2
2.2.2 SELEX data for protein targets
File File Size MD5 Digest
RNA_SELEX_data_for_RBM24.zip 14.52MB 3cfb3e12a876a1cbec56c11d5609f9b7
RNA_SELEX_data_for_RT.zip 1.69MB b758db8c80ff8148992dc37355b6531c
RNA_SELEX_data_for_S15.zip 22.13MB 4b196c0a8f32a3a9e18084c6bc4506d1
RNA_SELEX_data_for_TARDBP.zip 18.77MB b9467ab49f49613e2a6698051f377d03
2.2.3 SELEX data for (multi)cellular targets
File File Size MD5 Digest
RNA_SELEX_data_for_CHO-K1.zip 157.82MB 36c35b2a9dd5229b463a88fd9b72e74e
RNA_SELEX_data_for_ISLETS.zip 582.69MB b834d78ba28995710a29f57be83d863f
RNA_SELEX_data_for_MDSC.zip 223.34MB 804938060213ae3b0b483377e20dfa4b
RNA_SELEX_data_for_TNBC.zip 523.36MB 1189a02c76732914fda39ce7feadf91d

2.3 Dataset for fine-tuning in natural RNA evolution

2.3.1 human tissue-specific hallmarks of 3'-untranslated RNA
File File Size MD5 Digest
human_three_terminal_ncRNA.zip 207.49MB af0f710d3601a05bb1fdeb2677a47212